Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol: Neil1tm1Rsld Name: nei endonuclease VIII-like 1 (E. coli); targeted mutation 1, R Stephen Lloyd MGI ID: MGI:3620011 Synonyms: neil1- Gene: Neil1  Location: Chr9:57050084-57055589 bp, - strand  Genetic Position: Chr9, 30.89 cM, cytoband C Alliance: Neil1tm1Rsld page

Neil1tm1Rsld/Neil1tm1Rsld and wild-type mouse comparison Show the 2 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:106077
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion     A PGK-neo cassette was inserted into the coding region contained within exons 2 and 3. (J:106077)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Neil1 Mutation:	18 strains or lines available

Original:	J:106077 Vartanian V, et al., The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase. Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):1864-9
All:	11 reference(s)