Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Kcnab1tm1Mes
Name:	potassium voltage-gated channel, shaker-related subfamily, beta member 1; targeted mutation 1, Albee Messing
MGI ID:	MGI:3619233
Synonyms:	KvBeta1.1 null
Gene:	Kcnab1  Location: Chr3:64856636-65285643 bp, + strand  Genetic Position: Chr3, 30.15 cM
Alliance:	Kcnab1tm1Mes page

Germline Transmission:	Earliest citation of germline transmission: J:106453
Parent Cell Line:	AB1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 1a was replaced with a neomycin resistance cassette. The most abundant brain isoform was thus deleted while the primary heart isoform continued to be expressed. (J:106453)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kcnab1 Mutation:	27 strains or lines available

Original:	J:106453 Connor JX, et al., Genetic modifiers of the Kv beta2-null phenotype in mice. Genes Brain Behav. 2005 Mar;4(2):77-88
All:	1 reference(s)