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Ppardtm2Rev
Targeted Allele Detail
Summary
Symbol: Ppardtm2Rev
Name: peroxisome proliferator activator receptor delta; targeted mutation 2, Ronald M Evans
MGI ID: MGI:3616172
Synonyms: Ppardtm1.2Rev
Gene: Ppard  Location: Chr17:28451715-28520446 bp, + strand  Genetic Position: Chr17, 14.64 cM
Alliance: Ppardtm2Rev page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:105694
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe wild-type exon 4 is replaced with an in-frame lacZ gene upstream of the DNA binding domain. Although no evaluation of beta-galactosidase expression is published, we have been informed that beta-galactosidase expression has not been detected (personal communication). (J:133147)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ppard Mutation:  68 strains or lines available
References
Original:  J:105694 Barak Y, Creation of the allele Ppardtm1.2Rev. MGI Direct Data Submission. 2006;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory