Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mapk12tm1Cnd
Name:	mitogen-activated protein kinase 12; targeted mutation 1, Ana Cuenda
MGI ID:	MGI:3615494
Synonyms:	p38gamma-
Gene:	Mapk12  Location: Chr15:89014787-89024906 bp, - strand  Genetic Position: Chr15, 44.65 cM
Alliance:	Mapk12tm1Cnd page

Germline Transmission:	Earliest citation of germline transmission: J:105203
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance gene was inserted to replace exon 3 by homologous recombination. Immunoblot failed to detect protein in mutants. (J:105203)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mapk12 Mutation:	16 strains or lines available

Original:	J:105203 Sabio G, et al., p38gamma regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP. EMBO J. 2005 Mar 23;24(6):1134-45
All:	17 reference(s)