Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Hspa1btm1Bwy
Name:	heat shock protein 1B; targeted mutation 1, Byung-Woo Yoon
MGI ID:	MGI:3611984
Synonyms:	hsp70.1-
Gene:	Hspa1b  Location: Chr17:35175412-35178214 bp, - strand  Genetic Position: Chr17, 18.5 cM
Alliance:	Hspa1btm1Bwy page

Germline Transmission:	Earliest citation of germline transmission: J:103999
Parent Cell Line:	Other (see notes) (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A 1.9-kb neomycin resistance gene was inserted to replace the promoter and some of the coding sequences, including the ATG. Northern blot failed to detect transcriupt in mutant mice. (J:103999)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hspa1b Mutation:	23 strains or lines available

Original:	J:103999 Lee SH, et al., Targeted hsp70.1 disruption increases infarction volume after focal cerebral ischemia in mice. Stroke. 2001 Dec 1;32(12):2905-12
All:	2 reference(s)