Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Prlhrtm1Map
Name:	prolactin releasing hormone receptor; targeted mutation 1, Marc Parmentier
MGI ID:	MGI:3611903
Synonyms:	Gpr10-
Gene:	Prlhr  Location: Chr19:60455170-60456742 bp, - strand  Genetic Position: Chr19, 56.52 cM
Alliance:	Prlhrtm1Map page

Germline Transmission:	Earliest citation of germline transmission: J:103932
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Disruption caused by insertion of vector   Mutation details: A tau-lacZ fusion gene and a TK-neo cassette replaced the first 194 codons, sequence encoding transmembrane segments 1-4. Transcripts were not detected by RT-PCR in mutant mice. (J:103932)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prlhr Mutation:	17 strains or lines available

Original:	J:103932 Laurent P, et al., The prolactin-releasing peptide antagonizes the opioid system through its receptor GPR10. Nat Neurosci. 2005 Dec;8(12):1735-41
All:	1 reference(s)