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Rbm24 Gene Detail
Summary
  • Symbol
    Rbm24
  • Name
    RNA binding motif protein 24
  • Synonyms
    6330546B05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3610364
    NCBI Gene: 666794
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:46571910-46584571 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 23.61 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    55 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3610364
 protein coding gene Chr13:46571664-46584575 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020512
 protein coding gene Chr13:45183412-45198587 (+)
A/J MGP_AJ_G0020466
 protein coding gene Chr13:43616224-43630335 (+)
AKR/J MGP_AKRJ_G0020443
 protein coding gene Chr13:44814807-44829382 (+)
BALB/cJ MGP_BALBcJ_G0020462
 protein coding gene Chr13:43821136-43837290 (+)
C3H/HeJ MGP_C3HHeJ_G0020261
 protein coding gene Chr13:44681525-44695193 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020895
 protein coding gene Chr13:46567725-46581162 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018481
 protein coding gene Chr13:41660059-41672603 (+)
CAST/EiJ MGP_CASTEiJ_G0019776
 protein coding gene Chr13:44608091-44622190 (+)
CBA/J MGP_CBAJ_G0020222
 protein coding gene Chr13:48508781-48523994 (+)
DBA/2J MGP_DBA2J_G0020344
 protein coding gene Chr13:43177946-43192163 (+)
FVB/NJ MGP_FVBNJ_G0020323
 protein coding gene Chr13:42697112-42710850 (+)
LP/J MGP_LPJ_G0020419
 protein coding gene Chr13:45410522-45427126 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020352
 protein coding gene Chr13:48337188-48352922 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020938
 protein coding gene Chr13:44499370-44514362 (+)
PWK/PhJ MGP_PWKPhJ_G0019532
 protein coding gene Chr13:43300232-43313551 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019360
 protein coding gene Chr13:43173921-43186958 (+)
WSB/EiJ MGP_WSBEiJ_G0019838
 protein coding gene Chr13:44827964-44841473 (+)



Homology
more
  • Human Ortholog
    RBM24, RNA binding motif protein 24
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RBM24, RNA binding motif protein 24
  • Synonyms
    dJ259A10.1, RNPC6
  • Links
    NCBI Gene ID: 221662
    neXtProt AC: NX_Q9BX46
    UniProt: Q9BX46

  • Chr Location
    6p22.3; chr6:17281361-17293871 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with Rbm24 mouse models

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    20 phenotypes from 2 alleles in 2 genetic backgrounds
    3 phenotypes from multigenic genotypes
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit lethality between E12.5 and E13.5 with embryonic growth retardation, thin and unfused atrioventricular cushions, reduced myocardial trabeculation and increased apoptosis in the heart.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    48
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    887
  • Tissues
    84
  • cDNA Data
    34
  • Literature Summary
    10
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000038132 Ensembl Gene Model | MGI Sequence Detail 12662 C57BL/6J ±  kb
    transcript ENSMUST00000037923 Ensembl | MGI Sequence Detail 3086 Not Applicable  
    polypeptide ENSMUSP00000043120 Ensembl | MGI Sequence Detail 236 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 40
      cDNA 34
      Primer pair 3
      Other 3

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:1923426, MGI:2145271
    References
    more
    • Summaries
      All 44
      Developmental Gene Expression 10
      Diseases 1
      Gene Ontology 10
      Phenotypes 11
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:331878 Zhang J, et al., The RNA-binding protein RBM24 regulates lipid metabolism and SLC7A11 mRNA stability to modulate ferroptosis and inflammatory response. Front Cell Dev Biol. 2022;10:1008576
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory