Summary | Mutation origin | Mutation description | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Cacng8tm1Ran
Name:	calcium channel, voltage-dependent, gamma subunit 8; targeted mutation 1, Roger A Nicoll
MGI ID:	MGI:3609205
Synonyms:	gamma-8-, TARP gamma-8-
Gene:	Cacng8  Location: Chr7:3442558-3464782 bp, + strand  Genetic Position: Chr7, 1.98 cM
Alliance:	Cacng8tm1Ran page

Germline Transmission:	Earliest citation of germline transmission: J:102515
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The locus was disrupted by the replacement of exons 2 and 3 with a neomycin resistance gene. Quantitative immunoblot of hippocampal extracts of mutants confirms the absence of protein. (J:102515)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cacng8 Mutation:	31 strains or lines available

Original:	J:102515 Rouach N, et al., TARP gamma-8 controls hippocampal AMPA receptor number, distribution and synaptic plasticity. Nat Neurosci. 2005 Nov;8(11):1525-33
All:	10 reference(s)