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Prdm1tm2Rob
Targeted Allele Detail
Summary
Symbol: Prdm1tm2Rob
Name: PR domain containing 1, with ZNF domain; targeted mutation 2, Elizabeth J Robertson
MGI ID: MGI:3605483
Synonyms: prdm1BEH
Gene: Prdm1  Location: Chr10:44313173-44404497 bp, - strand  Genetic Position: Chr10, 23.24 cM
Alliance: Prdm1tm2Rob page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101718
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe insertion of a loxP flanked pgk-hygro cassette resulted in a deletion beginning upstream of the ATG in exon 1 and including exon 3. (J:101718)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 34 assay results
3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 8 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prdm1 Mutation:  64 strains or lines available
References
Original:  J:101718 Vincent SD, et al., The zinc finger transcriptional repressor Blimp1/Prdm1 is dispensable for early axis formation but is required for specification of primordial germ cells in the mouse. Development. 2005 Mar;132(6):1315-25
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory