Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Nectin3tm1Ytk
Name:	nectin cell adhesion molecule 3; targeted mutation 1, Yoshimi Takai
MGI ID:	MGI:3605481
Synonyms:	nectin 3-
Gene:	Nectin3  Location: Chr16:46208069-46318888 bp, - strand  Genetic Position: Chr16, 30.48 cM
Alliance:	Nectin3tm1Ytk page

Germline Transmission:	Earliest citation of germline transmission: J:101707
Parent Cell Line:	RW-4 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A construct was designed to replace sequence in exon 1 encoding amino acids1-58 with a neomycin resistance gene. Absence of protein was confirmed by Western blot. (J:101707)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	19 assay results
In Structures Affected by this Mutation:	8 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nectin3 Mutation:	44 strains or lines available

Original:	J:101707 Inagaki M, et al., Roles of cell-adhesion molecules nectin 1 and nectin 3 in ciliary body development. Development. 2005 Apr;132(7):1525-37
All:	11 reference(s)