Summary | Mutation origin | Mutation description | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Efna3tm1Rax
Name:	ephrin A3; targeted mutation 1, Richard Axel
MGI ID:	MGI:3605006
Gene:	Efna3  Location: Chr3:89221206-89230272 bp, - strand  Genetic Position: Chr3, 39.06 cM
Alliance:	Efna3tm1Rax page

Germline Transmission:	Earliest citation of germline transmission: J:101720
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S/SvEv

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 2-4 were replaced with a neomycin resistance cassette. The splicing of exon 1 to 5 would result in a frameshift encoding a protein truncated after 45 amino acids, lacking 90% of the ectodomain. (J:101720)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Efna3 Mutation:	10 strains or lines available

Original:	J:101720 Cutforth T, et al., Axonal ephrin-As and odorant receptors: coordinate determination of the olfactory sensory map. Cell. 2003 Aug 8;114(3):311-22
All:	13 reference(s)