Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | Notes | References

Symbol:	Gng7tm1Lex
Name:	guanine nucleotide binding protein (G protein), gamma 7; targeted mutation 1, Lexicon Genetics
MGI ID:	MGI:3604392
Synonyms:	Gng7-, Gng7tm1Rbs
Gene:	Gng7  Location: Chr10:80784463-80850742 bp, - strand  Genetic Position: Chr10, 39.72 cM
Alliance:	Gng7tm1Lex page

Germline Transmission:	Earliest citation of germline transmission: J:81988
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S/SvEvBrd
Project Collection:	Lexicon

Allele Type:    Targeted (Null/knockout) Mutation:    Not Specified   Mutation details: Coding exons 1 and 2 were targeted by homologous recombination. Neither transcript nor protein was detected in homozygous mutant brain tissue by RT-PCR and Western blot analyses. (J:81988, J:103485)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 1 line available
Carrying any Gng7 Mutation:	75 strains or lines available

Original:	J:81988 Schwindinger WF, et al., Loss of G protein gamma 7 alters behavior and reduces striatal alpha(olf) level and cAMP production. J Biol Chem. 2003 Feb 21;278(8):6575-9
All:	4 reference(s)