Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cxadrtm1Dvst
Name:	coxsackie virus and adenovirus receptor; targeted mutation 1, Dietmar Vestweber
MGI ID:	MGI:3587803
Synonyms:	CAR-
Gene:	Cxadr  Location: Chr16:78098377-78156662 bp, + strand  Genetic Position: Chr16, 45.28 cM, cytoband C
Alliance:	Cxadrtm1Dvst page

Germline Transmission:	Earliest citation of germline transmission: J:100174
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance cassette replaced exon 1, which contains the ATG start codon. Western blot of embryos failed to detect protein in mutants. (J:100174)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

8 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cxadr Mutation:	15 strains or lines available

Original:	J:100174 Dorner AA, et al., Coxsackievirus-adenovirus receptor (CAR) is essential for early embryonic cardiac development. J Cell Sci. 2005 Aug 1;118(Pt 15):3509-21
All:	1 reference(s)