Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Amd1tm1Kiga
Name:	S-adenosylmethionine decarboxylase 1; targeted mutation 1, Kazuei Igarashi
MGI ID:	MGI:3586494
Synonyms:	Amd1-
Gene:	Amd1  Location: Chr10:40163454-40178184 bp, - strand  Genetic Position: Chr10, 21.85 cM, cytoband B2
Alliance:	Amd1tm1Kiga page

Germline Transmission:	Earliest citation of germline transmission: J:99895
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: An EGFP-loxP-neo-loxP cDNA was inserted in frame to exon 1, downstream of the ATG. Northern blot and RT-PCR failed to detect transcript in mutant blastocysts. (J:99895)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Amd1 Mutation:	16 strains or lines available

Original:	J:99895 Nishimura K, et al., Essential role of S-adenosylmethionine decarboxylase in mouse embryonic development. Genes Cells. 2002 Jan;7(1):41-7
All:	1 reference(s)