Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Il3tm1Tyb
Name:	interleukin 3; targeted mutation 1, Victor L J Tybulewicz
MGI ID:	MGI:3586300
Synonyms:	Il3tm1Mur
Gene:	Il3  Location: Chr11:54156129-54158103 bp, - strand  Genetic Position: Chr11, 32.13 cM, cytoband B1
Alliance:	Il3tm1Tyb page

Germline Transmission:	Earliest citation of germline transmission: J:35829
Parent Cell Line:	D3 (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: As a result of a frameshift mutation in exon 1 and the deletion of exon 2, this allele lacks functional protein. (J:35829)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Il3 Mutation:	29 strains or lines available

Original:	J:35829 Nishinakamura R, et al., Hematopoiesis in mice lacking the entire granulocyte-macrophage colony-stimulating factor/interleukin-3/interleukin-5 functions. Blood. 1996 Oct 1;88(7):2458-64
All:	7 reference(s)