Summary | Mutation origin | Mutation description | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | References

Symbol:	Csf2tm1Dran
Name:	colony stimulating factor 2 (granulocyte-macrophage); targeted mutation 1, Glen Dranoff
MGI ID:	MGI:3586299
Synonyms:	GM-CSF -
Gene:	Csf2  Location: Chr11:54138097-54140493 bp, - strand  Genetic Position: Chr11, 32.13 cM
Alliance:	Csf2tm1Dran page

Germline Transmission:	Earliest citation of germline transmission: J:67404
Parent Cell Line:	D3 (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A hygromycin resistance cassette replaced exons 3 and 4 in an ES cell line in which the Il3 gene had already been targeted (MGI:2446538). Absence of protein was demonstrated immunologically. (J:67404)

View phenotypes and curated references for all genotypes (concatenated display).

List all tumor models in MMHCdb carrying Csf2tm1Dran

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Csf2 Mutation:	33 strains or lines available

Original:	J:67404 Gillessen S, et al., Overlapping roles for granulocyte-macrophage colony-stimulating factor and interleukin-3 in eosinophil homeostasis and contact hypersensitivity. Blood. 2001 Feb 15;97(4):922-8
All:	9 reference(s)