Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ppiftm1Maf
Name:	peptidylprolyl isomerase F (cyclophilin F); targeted mutation 1, Michael A Forte
MGI ID:	MGI:3586298
Synonyms:	CyPD-KO, Ppif-
Gene:	Ppif  Location: Chr14:25694578-25700892 bp, + strand  Genetic Position: Chr14, 15.06 cM
Alliance:	Ppiftm1Maf page

Germline Transmission:	Earliest citation of germline transmission: J:99922
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The insertion of a neomycin resistance cassette resulted in the deletion of the first three exons of the locus, including 20 bp upstream of the ATG. No protein was detected in mutant liver, kidney or heart samples. (J:99922)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ppif Mutation:	18 strains or lines available

Original:	J:99922 Basso E, et al., Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D. J Biol Chem. 2005 May 13;280(19):18558-61
All:	30 reference(s)