Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cd8atm1.1Litt
Name:	CD8 subunit alpha; targeted mutation 1.1, Dan R Littman
MGI ID:	MGI:3584478
Synonyms:	E8i delta
Gene:	Cd8a  Location: Chr6:71350411-71356155 bp, + strand  Genetic Position: Chr6, 32.14 cM, cytoband C
Alliance:	Cd8atm1.1Litt page

Germline Transmission:	Earliest citation of germline transmission: J:50624
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: This allele was derived from Cd8atm1Litt by crossing to mice expressing an unspecified CMV-cre transgene which results in germline excision of the floxed neomycin cassette. (J:50624)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd8a Mutation:	36 strains or lines available

Original:	J:50624 Ellmeier W, et al., Multiple developmental stage-specific enhancers regulate CD8 expression in developing thymocytes and in thymus-independent T cells. Immunity. 1998 Oct;9(4):485-96
All:	7 reference(s)