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Gna13tm2.1Cgh
Targeted Allele Detail
Summary
Symbol: Gna13tm2.1Cgh
Name: guanine nucleotide binding protein, alpha 13; targeted mutation 2.1, Shaun R Coughlin
MGI ID: MGI:3583877
Synonyms: delta4
Gene: Gna13  Location: Chr11:109253657-109292195 bp, + strand  Genetic Position: Chr11, 71.88 cM
Alliance: Gna13tm2.1Cgh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:99731
Parent Cell Line:  RF8 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsFloxed exon 4 was excised by breeding with mice bearing Tg(ACTB-cre)13Miya. This allele generates an mRNA fragment encoding a truncated protein predicted to be inactive and short-lived. (J:99731)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gna13 Mutation:  12 strains or lines available
References
Original:  J:99731 Ruppel KM, et al., Essential role for Galpha13 in endothelial cells during embryonic development. Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8281-6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory