Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Oclntm2Sts
Name:	occludin; targeted mutation 2, Shoichiro Tsukita
MGI ID:	MGI:3582579
Gene:	Ocln  Location: Chr13:100633015-100689226 bp, - strand  Genetic Position: Chr13, 53.23 cM
Alliance:	Oclntm2Sts page

Germline Transmission:	Earliest citation of germline transmission: J:99467
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 3 was replaced with a floxed neo cassette via homologous recombination. RT-PCR and western blot analysis confirmed the absence of mRNA and protein. (J:99467)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

10 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ocln Mutation:	33 strains or lines available

Original:	J:99467 Saitou M, et al., Complex phenotype of mice lacking occludin, a component of tight junction strands. Mol Biol Cell. 2000 Dec;11(12):4131-42
All:	5 reference(s)