Cma1<tm1Mfg> Targeted Allele Detail MGI Mouse (MGI:3581753)

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Cma1^tm1Mfg
Targeted Allele Detail

Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Cma1^tm1Mfg
Name:	chymase 1, mast cell; targeted mutation 1, Michael F Gurish
MGI ID:	MGI:3581753
Synonyms:	Mcpt5^-
Gene:	Cma1 Location: Chr14:56178908-56182132 bp, - strand Genetic Position: Chr14, 28.19 cM
Alliance:	Cma1^tm1Mfg page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:98963
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutation:		Insertion
		A neomycin resistance gene was inserted to the locus.

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Cma1 Mutation:	25 strains or lines available

References

Original:	J:98963 Abonia JP, et al., Mast cell protease 5 mediates ischemia-reperfusion injury of mouse skeletal muscle. J Immunol. 2005 Jun 1;174(11):7285-91
All:	4 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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