Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Slamf6tm1Dhow
Name:	SLAM family member 6; targeted mutation 1, Duncan Howie
MGI ID:	MGI:3581614
Synonyms:	Ly108deltaE2+3
Gene:	Slamf6  Location: Chr1:171745002-171776525 bp, + strand  Genetic Position: Chr1, 79.54 cM
Alliance:	Slamf6tm1Dhow page

Germline Transmission:	Earliest citation of germline transmission: J:98995
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129/Sv

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance gene replaced the second and third exons, which encode the complete ectodomain. RT-PCR of mutant thymus failed to detect transcript corresponding to exons 2 and 3. (J:98995)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slamf6 Mutation:	31 strains or lines available

Original:	J:98995 Howie D, et al., Cutting edge: the SLAM family receptor Ly108 controls T cell and neutrophil functions. J Immunol. 2005 May 15;174(10):5931-5
All:	5 reference(s)