Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Kcptm1Gdr
Name:	kielin/chordin-like protein; targeted mutation 1, Gregory R Dressler
MGI ID:	MGI:3579811
Synonyms:	Kcp-
Gene:	Kcp  Location: Chr6:29473161-29507951 bp, - strand  Genetic Position: Chr6, 12.36 cM
Alliance:	Kcptm1Gdr page

Germline Transmission:	Earliest citation of germline transmission: J:97529
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 2-21, encoding amino acids 67-774, were replaced with a lacZ-neomycin cassette. Absence of transcript in mutants was confirmed by Northern blot and RT-PCR. (J:97529)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Kcp Mutation:	58 strains or lines available

Original:	J:97529 Lin J, et al., Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic disease. Nat Med. 2005 Apr;11(4):387-93
All:	3 reference(s)