Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Fkbp4tm1Dvds
Name:	FK506 binding protein 4; targeted mutation 1, David F Smith
MGI ID:	MGI:3579432
Synonyms:	52KO, Fkbp52-
Gene:	Fkbp4  Location: Chr6:128407066-128415619 bp, - strand  Genetic Position: Chr6, 63.0 cM
Alliance:	Fkbp4tm1Dvds page

Germline Transmission:	Earliest citation of germline transmission: J:98554
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance gene replaced the entire coding sequence. Western blot failed to detect protein in thymic cytosol of mutants. (J:98554)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

8 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fkbp4 Mutation:	32 strains or lines available

Original:	J:98554 Cheung-Flynn J, et al., Physiological role for the cochaperone FKBP52 in androgen receptor signaling. Mol Endocrinol. 2005 Jun;19(6):1654-66
All:	10 reference(s)