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Kifap3tm1.1Noh
Targeted Allele Detail
Summary
Symbol: Kifap3tm1.1Noh
Name: kinesin-associated protein 3; targeted mutation 1.1, Nobutaka Hirokawa
MGI ID: MGI:3579410
Synonyms: Kap3-
Gene: Kifap3  Location: Chr1:163607152-163744678 bp, + strand  Genetic Position: Chr1, 71.08 cM, cytoband H1
Alliance: Kifap3tm1.1Noh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:98470
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele was derived from Kifap3tm1Noh. Cre recombinase excised exon 3 and produced a frame shift mutation that truncated the protein. Immunoblot of E14.5 brain lysates detected a significant loss of protein. (J:98470)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kifap3 Mutation:  53 strains or lines available
References
Original:  J:98470 Teng J, et al., The KIF3 motor transports N-cadherin and organizes the developing neuroepithelium. Nat Cell Biol. 2005 May;7(5):474-82
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory