Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Adamts4tm1.1Eam
Name:	ADAM metallopeptidase with thrombospondin type 1 motif 4; targeted mutation 1.1, Elisabeth A Morris
MGI ID:	MGI:3578001
Gene:	Adamts4  Location: Chr1:171077990-171088206 bp, + strand  Genetic Position: Chr1, 79.28 cM
Alliance:	Adamts4tm1.1Eam page

Germline Transmission:	Earliest citation of germline transmission: J:98327
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S/SvEvBrd

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: The floxed exon 4 was excised from Adamts4tm1Eam via cre-mediated recombination in the germline. RT-PCR confirmed the absence of exon 4 in mutant lung transcripts. (J:98327)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adamts4 Mutation:	48 strains or lines available

Original:	J:98327 Glasson SS, et al., Characterization of and osteoarthritis susceptibility in ADAMTS-4-knockout mice. Arthritis Rheum. 2004 Aug;50(8):2547-58
All:	2 reference(s)