Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ppiftm1Jmol
Name:	peptidylprolyl isomerase F (cyclophilin F); targeted mutation 1, Jeffery D Molkentin
MGI ID:	MGI:3577093
Synonyms:	Ppif-
Gene:	Ppif  Location: Chr14:25694578-25700892 bp, + strand  Genetic Position: Chr14, 15.06 cM
Alliance:	Ppiftm1Jmol page

Germline Transmission:	Earliest citation of germline transmission: J:97660
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance gene replaced the first three coding exons. Western blot of cardiac protein extracts from mutants demonstrated the lack of protein. (J:97660)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ppif Mutation:	18 strains or lines available

Original:	J:97660 Baines CP, et al., Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death. Nature. 2005 Mar 31;434(7033):658-62
All:	65 reference(s)