Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Raxtm1.2Lwd
Name:	retina and anterior neural fold homeobox; targeted mutation 1.2, Mark Lewandoski
MGI ID:	MGI:3576779
Synonyms:	Rxdelta2
Gene:	Rax  Location: Chr18:66067710-66072160 bp, - strand  Genetic Position: Chr18, 39.03 cM
Alliance:	Raxtm1.2Lwd page

Germline Transmission:	Earliest citation of germline transmission: J:97314
Parent Cell Line:	W9.5/W95 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Crossing Raxtm1Lwd mice with cre-deleter mice removed exon 2 in the germ line, leaving exon 3 out of frame and causing the creation of a truncated, nonfunctional protein lacking the homeodomain. (J:97314)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rax Mutation:	16 strains or lines available

Original:	J:97314 Voronina VA, et al., Conditional alleles for activation and inactivation of the mouse Rx homeobox gene. Genesis. 2005 Apr;41(4):160-4
All:	2 reference(s)