Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Xab2tm2Tnka
Name:	XPA binding protein 2; targeted mutation 2, Kiyoji Tanaka
MGI ID:	MGI:3574460
Synonyms:	XAB2-cd
Gene:	Xab2  Location: Chr8:3660089-3671311 bp, - strand  Genetic Position: Chr8, 1.92 cM
Alliance:	Xab2tm2Tnka page

Germline Transmission:	Earliest citation of germline transmission: J:96962
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Disruption caused by insertion of vector   Mutation details: A targeting vector was designed to delete the C-terminal 162 amino acids by replacing the 3' end of exon 14 and all of exons 15-19 with human HBB cDNA for exons 2 and 3. (J:96962)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Xab2 Mutation:	37 strains or lines available

Original:	J:96962 Yonemasu R, et al., Disruption of mouse XAB2 gene involved in pre-mRNA splicing, transcription and transcription-coupled DNA repair results in preimplantation lethality. DNA Repair (Amst). 2005 Apr 4;4(4):479-91
All:	1 reference(s)