Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cacna1gtm1.1Stl
Name:	calcium channel, voltage-dependent, T type, alpha 1G subunit; targeted mutation 1.1, Susumu Tonegawa
MGI ID:	MGI:3530501
Synonyms:	alpha1G KO
Gene:	Cacna1g  Location: Chr11:94299217-94365024 bp, - strand  Genetic Position: Chr11, 58.9 cM
Alliance:	Cacna1gtm1.1Stl page

Germline Transmission:	Earliest citation of germline transmission: J:96099
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Cacna1gtm1Stl mice were crossed with mice expressing cre in the germ line and produced this allele in which exons 9-12 were removed. In situ hybridization of mutant brains confirmed the complete loss of transcript. (J:96099)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cacna1g Mutation:	102 strains or lines available

Original:	J:96099 Anderson MP, et al., Thalamic Cav3.1 T-type Ca2+ channel plays a crucial role in stabilizing sleep. Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1743-8
All:	5 reference(s)