Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Srsf1tm1.1Xdfu
Name:	serine and arginine-rich splicing factor 1; targeted mutation 1.1, Xiang-Dong Fu
MGI ID:	MGI:3530159
Synonyms:	ASF/SF2-
Gene:	Srsf1  Location: Chr11:87938199-87944581 bp, + strand  Genetic Position: Chr11, 52.4 cM
Alliance:	Srsf1tm1.1Xdfu page

Germline Transmission:	Earliest citation of germline transmission: J:96039
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: This allele is produced from Sfrs1tm1Xdfu through cre recombinase in the oocyte resulting in deletion of exons 2 - 4 in the germline. (J:96039)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Srsf1 Mutation:	25 strains or lines available

Original:	J:96039 Xu X, et al., ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle. Cell. 2005 Jan 14;120(1):59-72
All:	1 reference(s)