Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Trpm1tm1Lex
Name:	transient receptor potential cation channel, subfamily M, member 1; targeted mutation 1, Lexicon Genetics
MGI ID:	MGI:3528857
Synonyms:	LexKO 428, TRPM1-
Gene:	Trpm1  Location: Chr7:63803583-63919523 bp, + strand  Genetic Position: Chr7, Syntenic
Alliance:	Trpm1tm1Lex page

Germline Transmission:	Earliest citation of germline transmission: J:154776
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S/SvEvBrd
Project Collection:	Lexicon

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     Exons 2-4 were replaced by a selection cassette resulting in a non-functional allele. (J:154776)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Trpm1 Mutation:	100 strains or lines available

Original:	J:154776 Morgans CW, et al., TRPM1 is required for the depolarizing light response in retinal ON-bipolar cells. Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19174-8
All:	22 reference(s)