Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Aqp7tm1Tfun
Name:	aquaporin 7; targeted mutation 1, Tohru Funahashi
MGI ID:	MGI:3526441
Synonyms:	Aqp7-
Gene:	Aqp7  Location: Chr4:41033074-41048139 bp, - strand  Genetic Position: Chr4, 20.83 cM, cytoband B1
Alliance:	Aqp7tm1Tfun page

Germline Transmission:	Earliest citation of germline transmission: J:95278
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neo cassette replaced 8 kb of sequence including exon 1-3 and the translation start sites. Northern blot analysis of WAT, BAT, kidney and liver of mutant mice demonstrated successful gene ablation. (J:95278)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Aqp7 Mutation:	24 strains or lines available

Original:	J:95278 Maeda N, et al., Adaptation to fasting by glycerol transport through aquaporin 7 in adipose tissue. Proc Natl Acad Sci U S A. 2004 Dec 21;101(51):17801-6
All:	5 reference(s)