Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Lgals3bptm1Megt
Name:	lectin, galactoside-binding, soluble, 3 binding protein; targeted mutation 1, Meg Trahey
MGI ID:	MGI:3522338
Synonyms:	CyCAP-
Gene:	Lgals3bp  Location: Chr11:118283573-118292787 bp, - strand  Genetic Position: Chr11, 83.14 cM, cytoband E
Alliance:	Lgals3bptm1Megt page

Germline Transmission:	Earliest citation of germline transmission: J:94936
Parent Cell Line:	E14.1a (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance gene replaced exons 3-6, leaving only the coding sequence for the first 27 amino acids. Northern blot of total RNA from kidney and liver of mutant mice showed that no transcript was present. (J:94936)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lgals3bp Mutation:	30 strains or lines available

Original:	J:94936 Trahey M, et al., Cyclophilin C-associated protein: a normal secreted glycoprotein that down-modulates endotoxin and proinflammatory responses in vivo. Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):3006-11
All:	2 reference(s)