Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ccr5tm1Sush
Name:	C-C motif chemokine receptor 5; targeted mutation 1, Kouji Matsushima
MGI ID:	MGI:3522335
Synonyms:	Ccr5-
Gene:	Ccr5  Location: Chr9:123921557-123934153 bp, + strand  Genetic Position: Chr9, 75.05 cM, cytoband F
Alliance:	Ccr5tm1Sush page

Germline Transmission:	Earliest citation of germline transmission: J:94937
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 2 was replaced by a neomycin resistance gene. RT-PCR comfirmed the lack of transcript in mutant lymphocytes. (J:94937)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ccr5 Mutation:	29 strains or lines available

Original:	J:94937 Murai M, et al., Peyer's patch is the essential site in initiating murine acute and lethal graft-versus-host reaction. Nat Immunol. 2003 Feb;4(2):154-60
All:	22 reference(s)