Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hoxb6tm1Cka
Name:	homeobox B6; targeted mutation 1, Claudia Kappen
MGI ID:	MGI:3514269
Synonyms:	Hoxb-6hd
Gene:	Hoxb6  Location: Chr11:96183647-96192395 bp, + strand  Genetic Position: Chr11, 59.82 cM
Alliance:	Hoxb6tm1Cka page

Germline Transmission:	Earliest citation of germline transmission: J:133561
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The part of exon 2 that encodes the homeobox and the exon 2 splice acceptor site was replaced with a neo cassette. (J:133561)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Hoxb6 Mutation:	14 strains or lines available

Original:	J:133561 Kappen C, Disruption of the homeobox gene Hoxb-6 in mice results in increased numbers of early erythrocyte progenitors. Am J Hematol. 2000 Oct;65(2):111-8
All:	2 reference(s)