About   Help   FAQ
Park7tm1Tmd
Targeted Allele Detail
Summary
Symbol: Park7tm1Tmd
Name: Parkinson disease (autosomal recessive, early onset) 7; targeted mutation 1, Ted Dawson
MGI ID: MGI:3514165
Synonyms: DJ-1-
Gene: Park7  Location: Chr4:150981590-150994378 bp, - strand  Genetic Position: Chr4, 81.52 cM, cytoband E1
Alliance: Park7tm1Tmd page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:125021
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA floxed neomycin resistance cassette replaced part of exon 2 and all of exon 3. Absence of protein product was confirmed by immunohistochemistry and western blot analysis. (J:125021)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Park7 Mutation:  53 strains or lines available
References
Original:  J:125021 Andres-Mateos E, et al., DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14807-12
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/12/2024
MGI 6.23
The Jackson Laboratory