Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Lalbatm1Jvt
Name:	lactalbumin, alpha; targeted mutation 1, J L Vilotte
MGI ID:	MGI:3513842
Synonyms:	Alphalac-
Gene:	Lalba  Location: Chr15:98378281-98380602 bp, - strand  Genetic Position: Chr15, 54.48 cM
Alliance:	Lalbatm1Jvt page

Germline Transmission:	Earliest citation of germline transmission: J:19377
Parent Cell Line:	D3 (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: An HSV-neo replaced the region spanning 0.56 kb of the 5' flanking sequence to the transcription region upstream from intron 2. Northern blot revealed an absence of mRNA in mammary gland of mutant mice and Western blot confirmed the absence of protein. (J:19377)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lalba Mutation:	8 strains or lines available

Original:	J:19377 Stinnakre MG, et al., Creation and phenotypic analysis of alpha-lactalbumin-deficient mice. Proc Natl Acad Sci U S A. 1994 Jul 5;91(14):6544-8
All:	1 reference(s)