Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Sypl2tm1Hta
Name:	synaptophysin like 2; targeted mutation 1, Hiroshi Takeshima
MGI ID:	MGI:3513758
Synonyms:	MG29m1
Gene:	Sypl2  Location: Chr3:108119582-108133915 bp, - strand  Genetic Position: Chr3, 46.87 cM, cytoband F3-H2
Alliance:	Sypl2tm1Hta page

Germline Transmission:	Earliest citation of germline transmission: J:59188
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The promoter and the first exon were replaced by a neomycin selection cassette. Northern and western blot analysis were used to demonstrate an absence of transcript and protein encoded by this gene. (J:59188)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sypl2 Mutation:	21 strains or lines available

Original:	J:59188 Nishi M, et al., Abnormal features in skeletal muscle from mice lacking mitsugumin29. J Cell Biol. 1999 Dec 27;147(7):1473-80
All:	5 reference(s)