Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cyp2g1tm1Ding
Name:	cytochrome P450, family 2, subfamily g, polypeptide 1; targeted mutation 1, Xinxin Ding
MGI ID:	MGI:3512181
Gene:	Cyp2g1  Location: Chr7:26508352-26520622 bp, + strand  Genetic Position: Chr7, 15.5 cM, cytoband A3
Alliance:	Cyp2g1tm1Ding page

Germline Transmission:	Earliest citation of germline transmission: J:94380
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 3 was replaced with a neomycin resistance gene cassette. Absence of transcript expression was confirmed by Northern blot analysis. The inserted neo cassette also reduced the expression of the neighboring Cyp2a5 gene. (J:94380)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cyp2g1 Mutation:	27 strains or lines available

Original:	J:94380 Zhuo X, et al., Targeted disruption of the olfactory mucosa-specific Cyp2g1 gene: impact on acetaminophen toxicity in the lateral nasal gland, and tissue-selective effects on Cyp2a5 expression. J Pharmacol Exp Ther. 2004 Feb;308(2):719-28
All:	2 reference(s)