Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rac3tm1Hkp
Name:	Rac family small GTPase 3; targeted mutation 1, Nora C Hesterkamp
MGI ID:	MGI:3512107
Gene:	Rac3  Location: Chr11:120612296-120614795 bp, + strand  Genetic Position: Chr11, 84.46 cM
Alliance:	Rac3tm1Hkp page

Germline Transmission:	Earliest citation of germline transmission: J:99168
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The entire coding region was replaced with a PGK-NEO cassette. QRT-PCR confirmed the absence of gene products. (J:99168)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rac3 Mutation:	13 strains or lines available

Original:	J:99168 Cho YJ, et al., Generation of rac3 Null Mutant Mice: Role of Rac3 in Bcr/Abl-Caused Lymphoblastic Leukemia. Mol Cell Biol. 2005 Jul;25(13):5777-85
All:	2 reference(s)