Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | References

Symbol:	Ddb2tm1Pra
Name:	damage specific DNA binding protein 2; targeted mutation 1, Pradip Raychaudhuri
MGI ID:	MGI:3511965
Synonyms:	DDB2-
Gene:	Ddb2  Location: Chr2:91041917-91067327 bp, - strand  Genetic Position: Chr2, 50.56 cM, cytoband E1
Alliance:	Ddb2tm1Pra page

Germline Transmission:	Earliest citation of germline transmission: J:95633
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 4 and 5 were replaced with a neomycin selection cassette. Gene expression could not be detected by RT-PCR assay. (J:95633)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

List all tumor models in MMHCdb carrying Ddb2tm1Pra

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ddb2 Mutation:	38 strains or lines available

Original:	J:95633 Yoon T, et al., Tumor-prone phenotype of the DDB2-deficient mice. Oncogene. 2005 Jan 13;24(3):469-78
All:	6 reference(s)