Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Slc3a2tm1Yai
Name:	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2; targeted mutation 1, Yasuhiko Ito
MGI ID:	MGI:3511126
Synonyms:	CD98-
Gene:	Slc3a2  Location: Chr19:8684931-8700733 bp, - strand  Genetic Position: Chr19, 5.44 cM
Alliance:	Slc3a2tm1Yai page

Germline Transmission:	Earliest citation of germline transmission: J:93968
Parent Cell Line:	RW-4 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: Aberrant recombination resulted in the insertion of a neo cassette between intron 2 and the 5' arm of the heavy chain. Northern blot analysis showed the presence of an aberrant transcript in heterozygous mice. (J:93968)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc3a2 Mutation:	37 strains or lines available

Original:	J:93968 Tsumura H, et al., The targeted disruption of the CD98 gene results in embryonic lethality. Biochem Biophys Res Commun. 2003 Sep 5;308(4):847-51
All:	2 reference(s)