Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gcgrtm1Mjch
Name:	glucagon receptor; targeted mutation 1, M J Charron
MGI ID:	MGI:3505881
Synonyms:	Gcgr-
Gene:	Gcgr  Location: Chr11:120421525-120429812 bp, + strand  Genetic Position: Chr11, 84.24 cM, cytoband E2
Alliance:	Gcgrtm1Mjch page

Germline Transmission:	Earliest citation of germline transmission: J:81772
Parent Cell Line:	WW6 (ES Cell)
Strain of Origin:	STOCK 129/Sv and C57BL/6J and SJL

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     Exons 3-6 were replaced with a PGK-neo. (J:81772)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	24 assay results
In Structures Affected by this Mutation:	8 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gcgr Mutation:	5 strains or lines available

Original:	J:81772 Gelling RW, et al., Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice. Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1438-43
All:	43 reference(s)