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Cnr1tm1Ojm
Targeted Allele Detail
Summary
Symbol: Cnr1tm1Ojm
Name: cannabinoid receptor 1; targeted mutation 1, Olivier J Manzoni
MGI ID: MGI:3505551
Synonyms: CB1-
Gene: Cnr1  Location: Chr4:33924593-33948831 bp, + strand  Genetic Position: Chr4, 16.28 cM
Alliance: Cnr1tm1Ojm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:93698
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance gene replaced the sequence spanning from part of the 5' UTR to the sixth transmembrane region. (J:93698)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cnr1 Mutation:  43 strains or lines available
References
Original:  J:93698 Robbe D, et al., Endogenous cannabinoids mediate long-term synaptic depression in the nucleus accumbens. Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8384-8
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory