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Ago2tm1Ghan
Targeted Allele Detail
Summary
Symbol: Ago2tm1Ghan
Name: argonaute RISC catalytic subunit 2; targeted mutation 1, Greggory J Hannon
MGI ID: MGI:3056454
Synonyms: Ago2-
Gene: Ago2  Location: Chr15:72967693-73056777 bp, - strand  Genetic Position: Chr15, 33.92 cM
Alliance: Ago2tm1Ghan page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:93081
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Duplication, Insertion
  Ago2tm1Ghan involves 1 genes/genome features (Ago2) View all
 
Mutation detailsA targeting vector was designed to insert a PGK-neo and a duplicate of exons 3-6 into the endogenous locus. No mRNA was detected by RT-PCR. (J:93081)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ago2 Mutation:  54 strains or lines available
References
Original:  J:93081 Liu J, et al., Argonaute2 is the catalytic engine of mammalian RNAi. Science. 2004 Sep 3;305(5689):1437-41
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory