About   Help   FAQ
Rasd1tm1Pngr
Targeted Allele Detail
Summary
Symbol: Rasd1tm1Pngr
Name: RAS, dexamethasone-induced 1; targeted mutation 1, Josef M Penninger
MGI ID: MGI:3054834
Synonyms: dexras1-
Gene: Rasd1  Location: Chr11:59854007-59855770 bp, - strand  Genetic Position: Chr11, 37.81 cM, cytoband B2
Alliance: Rasd1tm1Pngr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:92624
Parent Cell Line:  E14K (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsNucleotides encoding amino acids 13-227 were replaced with a neomycin resistance gene. The deleted sequence encompassed the GTP binding and hydrolysis domain and the effector loop. Transcripts were undetectable in RT-PCR or Northern blot of mutant brain tissue. (J:92624)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rasd1 Mutation:  15 strains or lines available
References
Original:  J:92624 Cheng HY, et al., Dexras1 potentiates photic and suppresses nonphotic responses of the circadian clock. Neuron. 2004 Sep 2;43(5):715-28
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/12/2024
MGI 6.23
The Jackson Laboratory