Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Chst2tm1Tmu
Name:	carbohydrate sulfotransferase 2; targeted mutation 1, Takashi Muramatsu
MGI ID:	MGI:3052713
Synonyms:	GlcNAc6ST-1, Gn6st-, GST2-
Gene:	Chst2  Location: Chr9:95282979-95289323 bp, - strand  Genetic Position: Chr9, 50.11 cM, cytoband E3.2-3.3
Alliance:	Chst2tm1Tmu page

Germline Transmission:	Earliest citation of germline transmission: J:92231
Parent Cell Line:	D3 (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The 3' PAPS binding region in the catalytic domain was replaced with a neomycin resistance gene. Southern blot confirmed recombination and RT-PCR indicated no transcript was detected in mutant organs. (J:92231)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Chst2 Mutation:	21 strains or lines available

Original:	J:92231 Uchimura K, et al., N-acetylglucosamine 6-O-sulfotransferase-1 regulates expression of L-selectin ligands and lymphocyte homing. J Biol Chem. 2004 Aug 13;279(33):35001-8
All:	17 reference(s)