Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gabpatm1Rist
Name:	GA repeat binding protein, alpha; targeted mutation 1, Sika Ristevski
MGI ID:	MGI:3050761
Synonyms:	Gapbalpha-
Gene:	Gabpa  Location: Chr16:84631813-84660667 bp, + strand  Genetic Position: Chr16, 46.92 cM, cytoband C3-4
Alliance:	Gabpatm1Rist page

Germline Transmission:	Earliest citation of germline transmission: J:91600
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: An IRES-lacZ-neo-pA cassette was inserted to disrupt exon 2, the first coding exon. Southern blot and PCR confirmed recombination. Western blot indicates comparable levels of proteins in wild-type and heterozygous ES cells. (J:91600)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gabpa Mutation:	66 strains or lines available

Original:	J:91600 Ristevski S, et al., The ETS transcription factor GABPalpha is essential for early embryogenesis. Mol Cell Biol. 2004 Jul;24(13):5844-9
All:	1 reference(s)