Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Bach2tm1Igar
Name:	BTB and CNC homology, basic leucine zipper transcription factor 2; targeted mutation 1, Kazuhiko Igarashi
MGI ID:	MGI:3047541
Synonyms:	Bach2-
Gene:	Bach2  Location: Chr4:32238804-32586108 bp, + strand  Genetic Position: Chr4, 14.02 cM, cytoband A4
Alliance:	Bach2tm1Igar page

Germline Transmission:	Earliest citation of germline transmission: J:91110
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The first coding exon was replaced with a floxed neo and lacZ gene cassette. Southern blot confirmed recombination and Western blot of bone marrow B cell did not detect protein in mutants. (J:91110)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bach2 Mutation:	44 strains or lines available

Original:	J:91110 Muto A, et al., The transcriptional programme of antibody class switching involves the repressor Bach2. Nature. 2004 Jun 3;429(6991):566-71
All:	23 reference(s)